| Pair Name | Epsilon-Viniferin, alpha-Viniferin | ||
| Phytochemical Name | Epsilon-Viniferin (PubChem CID: 5281728 ) | ||
| Anticancer drug Name | alpha-Viniferin (PubChem CID: 196402 ) | ||
| Structure of Phytochemical |
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| Structure of Anticancer Drug |
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| Pair Name | Epsilon-Viniferin, alpha-Viniferin | |||
| Disease Info | [ICD-11: 2C25] | Lung cancer | Investigative | |
| Biological Phenomena | Induction-->Apoptosis | |||
| Gene Regulation | Down-regulation | Phosphorylation | AKT1 | hsa207 |
| Up-regulation | Cleavage | CASP3 | hsa836 | |
| Down-regulation | Phosphorylation | MAPK8 | hsa5599 | |
| Down-regulation | Phosphorylation | MAPK9 | hsa5601 | |
| Up-regulation | Cleavage | PARP1 | hsa142 | |
| In Vitro Model | A-549 | Lung adenocarcinoma | Homo sapiens (Human) | CVCL_0023 |
| Result | ε-viniferin and α-viniferin may prove to be new approaches and effective therapeutic agents for osteosarcoma and lung cancer treatment. | |||
| No. | Title | Href |
|---|---|---|
| 1 | ε-Viniferin and α-viniferin alone or in combination induced apoptosis and necrosis in osteosarcoma and non-small cell lung cancer cells. Food Chem Toxicol. 2021;158:112617. doi:10.1016/j.fct.2021.112617. | Click |
